Novel porous β-CD polymer was prepared and used for rapid removal of organic micropollutants from water. The crosslinking agent, tetrafluoroterephthalonitrile ensures rigid structure and high porosity improving the availability of the CD rings within the structure. Even mixtures of emerging contaminants (drugs, hormones, pesticides and endocrine-disrupting chemicals) were efficiently removed in the flow-through laboratory demonstration using 0.3 g sorbent for 8 mL model solution of micropollutants.