Sulfobutylether Beta Cyclodextrin Sodium ( Betadex Sulfobutylether Sodium, SBE-β-CD ) has a side chain with negative charge, which has a special force on positively charged drugs. The inclusion of hydrophobic drugs can improve the water solubility of drugs, increase the absorption of drugs in the body, and improve the stability. 
In addition, it can well form non-covalent complexes with drug molecules, thereby improving the safety of drugs, reducing renal toxicity, alleviating drug hemolysis, controlling drug release rate, and covering up unpleasant smells.
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